health

Lograron eliminar por completo tumores de páncreas en ratones utilizando una triple terapia

Hace cinco años, el equipo de Mariano Barbacid, director del Grupo de Oncología Experimental del Centro Nacional de Investigaciones Oncológicas (CNIO) de España, daba […]

Lograron eliminar por completo tumores de páncreas en ratones utilizando una triple terapia

TL;DR

  • Researchers at CNIO have developed a triple therapy for pancreatic cancer.
  • The therapy has shown efficacy in mouse models of pancreatic ductal adenocarcinoma (PDAC).
  • It targets the KRAS oncogene, EGFR, and STAT3.
  • The treatment resulted in the complete disappearance of tumor cells and stroma.
  • Tumors in mouse models, including patient-derived xenografts (PDX), were eliminated.
  • The therapy demonstrated durability, with animals remaining disease-free for over 200 days post-treatment.
  • No significant side effects were observed.
  • The research was funded by CRIS Contra el Cáncer.

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